Cannot access webmail

I have completed the EE install including mail package etc however cannot access Roundcube. I wanted to get my email up and running for my 1st domain. When I go to it just times out and then page cannot be displayed. I have a CNAME for webmail to my domain in my DNS. Should I be able to access the webmail with localhost? That does not work either.

Additional notes: I’ve created a website and that is working fine. Sending email seems to work fine. I can also access all EE tools.

My hostname (computer name) is different than my website domain names but do I need to point DNS to that as well for this to work? I’m self hosting with a static IP and port forwarding.